Police are investigating after a serious collision in Berwick on Sunday 17 December.
Emergency services were called to the outbound lanes of the Monash Freeway near Narre Warren North Road to reports a white Toyota Corolla sedan had collided with a Kia Sportage SUV about 5.05pm.
The Kia rolled as a result of the impact and came to rest on its side, off the edge of the road.
The driver of the Kia, a 30-year-old Clyde woman, was flown to hospital with non-life-threatening injuries.
Three passengers from the Kia were also taken to hospital.
A 31-year-old Clyde man was taken to hospital with non-life-threatening injuries.
54-year-old Berwick woman was taken to hospital with non-life-threatening injuries.
A 15-month-old girl from Clyde was not seriously injured and taken to hospital for observation.
The driver of the Toyota, a 16-year-old Clyde North boy, sustained minor injuries and was taken to hospital under police guard.
The exact circumstances surrounding the collision are yet to be determined and investigations remain ongoing.
Police are appealing for anyone who witnessed the incident or has dashcam footage to come forward.
Investigators are also interested in anyone with information on the movements of the Toyota Corolla prior to the collision.
Anyone who can assist police with their enquiries is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at crimestoppersvic.com.au